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Article

Prognostic and predictive role of vascular endothelial growth factor polymorphisms in breast cancer.

Pharmacogenomics - 1 Jan 2015

Koutras Angelos, Kotoula Vasiliki, Fountzilas George

Abstract excerpt

Current evidence indicates that angiogenesis plays an important role in the pathogenesis of several malignancies, including breast cancer. The vascular endothelial growth factor (VEGF) pathway has been investigated extensively, due to its important role in angiogenesis. The major mediator of tumor angiogenesis is VEGF-A, frequently referred to as VEGF, which activates the VEGF receptor-2. The VEGF gene is located...

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Share to Breast Neoplasms
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Neovascularization, Pathologic

Share to Polymorphism, Single Nucleotide

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Share to Vascular Endothelial Growth Factor A

Share to Vascular Endothelial Growth Factor Receptor-2

Source

Identifiers

PMID: 25560472
DOI: 10.2217/pgs.14.148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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