Article
VEGFA gene variants are associated with breast cancer progression.
The journal of pathology. Clinical research - 1 Sept 2024
Furriol Jessica, Wik Elisabeth, Aziz Sura, Askeland Cecilie, Knutsvik Gøril, Akslen Lars A
Abstract excerpt
Angiogenesis is recognized as a hallmark of cancer, and vascular endothelial growth factor (VEGF) is a key regulator of the angiogenic process and is related to cancer progression. Anti-VEGF therapy has been tried but with limited success and without useful stratification for angiogenesis markers...
Topics
- Humans
- Breast Neoplasms
- Female
- Vascular Endothelial Growth Factor A
- Polymorphism, Single Nucleotide
- Disease Progression
- Middle Aged
- Neovascularization, Pathologic
- Biomarkers, Tumor
- Aged
- Adult
- Genotype
- Genetic Predisposition to Disease