Article
VEGFA gene variants are associated with breast cancer progression.
The journal of pathology. Clinical research - 1 Sept 2024
Furriol Jessica, Wik Elisabeth, Aziz Sura, Askeland Cecilie, Knutsvik Gøril, Akslen Lars A
Abstract excerpt
Angiogenesis is recognized as a hallmark of cancer, and vascular endothelial growth factor (VEGF) is a key regulator of the angiogenic process and is related to cancer progression. Anti-VEGF therapy has been tried but with limited success and without useful stratification for angiogenesis markers. Further, the landscape of VEGF single nucleotide polymorphisms (SNPs) in breast cancer and their clinical relevance...
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