Article
Prognostic evaluation of VEGFA genotypes and haplotypes in a cohort of Brazilian women with non metastatic breast cancer.
Cancer biology & therapy - 2 Jun 2016
Vieira-Monteiro Hayra de Andrade, Freitas-Alves Daniely Regina, Sobral-Leite Marcelo, Delou João Marcos de Azevedo, Goulart-Citrangulo Sheyla Maria Torres, do Nascimento Camila Telles, E Castro Thales Nascimento, Koifman Sérgio, Perini Jamila Alessandra, Vianna-Jorge Rosane
Abstract excerpt
Vascular Endothelial Growth Factor (VEGF) mediates angiogenesis, which is crucial for tumor development and progression. The present study aimed to evaluate the impact of VEGFA gene polymorphisms rs699947, rs833061, rs1570360, rs2010963 and rs3025039 on breast cancer features and prognosis. A cohort of Brazilian women (N = 1038) with unilateral non-metastatic breast cancer was evaluated. The association between...
