Article
The R-spondin family of proteins: emerging regulators of WNT signaling.
The international journal of biochemistry & cell biology - 1 Dec 2012
Jin Yong-Ri, Yoon Jeong Kyo
Abstract excerpt
Recently, the R-spondin (RSPO) family of proteins has emerged as important regulators of WNT signaling. Considering the wide spectrum of WNT signaling functions in normal biological processes and disease conditions, there has been a significantly growing interest in understanding the functional roles of RSPOs in multiple biological processes and determining the molecular mechanisms by which RSPOs regulate the WNT...
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