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Article

Genetic polymorphisms of drug metabolizing enzymes and transporters: the long way from bench to bedside.

Current topics in medicinal chemistry - 1 Jan 2012

Evrard Alexandre, Mbatchi Litaty

Abstract excerpt

Pharmacogenetics has progressively become a major concern in personalized medicine. The development of modern technologies in genetic testing and cost-effectiveness have rendered genotyping strategies easy to perform comparing to time-consuming phenotyping methods. In oncology, canonical markers such TPMT, DPYD or UGT1A1 are routinely included in clinical practice but their use is still controversial partly...

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Identifiers

PMID: 22978342
DOI: 10.2174/156802612803531388

Genes

CDA
DPYD
TPMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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