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Article

Pharmacogenetics of drug metabolising enzymes: importance for personalised medicine.

Clinical chemistry and laboratory medicine - 1 Apr 2003

Oscarson Mikael

Abstract excerpt

The number of polymorphisms identified in genes encoding drug metabolising enzymes, drug transporters, and receptors is rapidly increasing. In many cases, these genetic factors have a major impact on the pharmacokinetics and pharmacodynamics of a particular drug and thereby influence the sensitivity to such drug in an individual patient with a certain genotype. The highest impact is seen for drugs with a narrow...

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Identifiers

PMID: 12747605
DOI: 10.1515/CCLM.2003.087

Genes

TPMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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