Article
How to manage individualized drug therapy: application of pharmacogenetic knowledge of drug metabolism and transport.
Clinical chemistry and laboratory medicine - 1 Sept 2000
Meisel C, Roots I, Cascorbi I, Brinkmann U, Brockmöller J
Abstract excerpt
Significant fractions of health budgets must be spent for treatment of drug side effects and for inefficient drug therapy. Hereditary variants in drug metabolizing enzymes, drug transporters, and drug targets are important determinants of drug response and toxicity and may therefore aid in select...
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