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Article

Clinical Pharmacogenetics and Potential Application in Personalized Medicine

1 Oct 2008

Abstract excerpt

The current 'fixed-dosage strategy' approach to medicine, means there is much inter-individual variation in drug response. Pharmacogenetics is the study of how inter-individual variations in the DNA sequence of specific genes affect drug responses. This article will highlight current pharmacogenetic knowledge on important drug metabolizing enzymes, drug transporters and drug targets to understand interindividual...

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PMID: 18855611
DOI: 10.2174/138920008786049302

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