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Article

[State of the art of pharmacogenetic diagnostics in drug therapy].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - 1 Oct 2006

Kirchheiner J, Seeringer A, Brockmöller J

Abstract excerpt

Individual differences in the effect and side effect of drugs are partly due to genetic factors (genetic polymorphisms). The responsible polymorphisms lie in genes encoding for drug metabolism and transport but also in direct and indirect drug targets. While genetic variants in pharmacokinetic structures exert effects on drug efficacy via the differences in drug exposure, polymorphisms in drug targets can...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17013776
DOI: 10.1007/s00103-006-0045-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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