Article
DMET™ (Drug Metabolism Enzymes and Transporters): a pharmacogenomic platform for precision medicine.
Oncotarget - 16 Aug 2016
Arbitrio Mariamena, Di Martino Maria Teresa, Scionti Francesca, Agapito Giuseppe, Guzzi Pietro Hiram, Cannataro Mario, Tassone Pierfrancesco, Tagliaferri Pierosandro
Abstract excerpt
In the era of personalized medicine, high-throughput technologies have allowed the investigation of genetic variations underlying the inter-individual variability in drug pharmacokinetics/pharmacodynamics. Several studies have recently moved from a candidate gene-based pharmacogenetic approach to genome-wide pharmacogenomic analyses to identify biomarkers for selection of patient-tailored therapies. In this aim,...
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