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Article

Germline oncopharmacogenetics, a promising field in cancer therapy.

Cellular oncology (Dordrecht, Netherlands) - 1 Feb 2015

Pesenti Chiara, Gusella Milena, Sirchia Silvia M, Miozzo Monica

Abstract excerpt

Pharmacogenetics (PGx) is the study of the relationship between inter-individual genetic variation and drug responses. Germline variants of genes involved in drug metabolism, drug transport, and drug targets can affect individual response to medications. Cancer therapies are characterized by an intrinsically high toxicity; therefore, the application of pharmacogenetics to cancer patients is a particularly...

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Identifiers

PMID: 25573079
DOI: 10.1007/s13402-014-0214-4
PMCID: PMC13004258

Genes

DPYD
G6PD
TPMT
UGT1A1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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