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MxA polymorphisms are associated with risk and age-at-onset in Alzheimer disease and accelerated cognitive decline in Chinese elders.

Rejuvenation research - 1 Oct 2012

Ma Suk Ling, Huang Wei, Tang Nelson L S, Lam Linda C W

Abstract excerpt

Alzheimer disease (AD) is the most common neurodegenerative disease, and inflammation has been associated with the pathogenesis of AD. The myxovirus resistance protein 1 (MxA) is an interferon-induced antiviral protein and is widely studied in virus-caused diseases. An immunohistochemical study has shown MxA expression in senile plaques of the AD brain, suggesting that MxA might be involved in the pathogenesis of...

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PMID: 22950423
DOI: 10.1089/rej.2012.1328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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