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Article

TREM1 mRNA Expression in Leukocytes and Cognitive Function in Japanese Patients with Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2018

Sao Tomoko, Yoshino Yuta, Yamazaki Kiyohiro, Ozaki Yuki, Mori Yoko, Ochi Shinichiro, Yoshida Taku, Mori Takaaki, Iga Jun-Ichi, Ueno Shu-Ichi

Abstract excerpt

BACKGROUND: Triggering receptor expressed on myeloid cells 2 (TREM2) activates the innate immune system, promotes phagocytosis by microglia, and is associated with Alzheimer's disease (AD). The possible role of a related molecule, TREM1, in AD remains unknown. OBJECTIVE: We investigated a possible role for TREM1 in AD by determining the gene expression and methylation levels of TREM1 in leukocytes from AD...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30010135
DOI: 10.3233/JAD-180418

Genes

TREM1
APOE
TREM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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