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DNMT3A rs1550117 Polymorphism is Associated With Late-Onset Alzheimer's Disease in a Chinese Population.

American journal of Alzheimer's disease and other dementias - 1 May 2016

Ling Chen, Fangyu Dai, Wanhua Hu, Kelong Chen, Zhimin Wu, Yuting Zhang, Rong Zhou

Abstract excerpt

Alzheimer's disease (AD) is classified as a neurodegenerative disease, impacting on brain integrity and functioning, resulting in a progressive deterioration of cognitive capabilities. Epigenetic changes can be acquired over the life span and mediate environmental effects on gene expression. DNA-methyltransferase 3A (DNMT3A) plays an important role in the development of embryogenesis and the generation of...

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Identifiers

PMID: 26371346
DOI: 10.1177/1533317515603688
PMCID: PMC10852886

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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