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Article

Immunoglobulin gene conversion: insights from bursal B cells and the DT40 cell line.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2004

Arakawa Hiroshi, Buerstedde Jean-Marie

Abstract excerpt

Chicken B cells diversify their immunoglobulin (Ig) light and heavy chain genes by pseudogene templated gene conversion within the bursa of Fabricius. Although Ig gene conversion was initially believed to occur only in birds, it is now clear that most farm animals also use this elegant mechanism to develop an immunoglobulin gene repertoire. The best model to study Ig gene conversion remains the chicken Ig light...

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Identifiers

PMID: 14991701
DOI: 10.1002/dvdy.10495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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