Article
Value of platelet pharmacogenetics in common clinical practice of patients with ST-segment elevation myocardial infarction.
International journal of cardiology - 10 Sept 2013
Verschuren Jeffrey J W, Boden Helèn, Wessels Judith A M, van der Hoeven Bas L, Trompet Stella, Heijmans Bastiaan T, Putter Hein, Guchelaar Henk-Jan, Schalij Martin J, Jukema J Wouter
Abstract excerpt
BACKGROUND: Antiplatelet drug resistance is a well-known problem, causing recurrent cardiovascular events. Multiple genetic polymorphisms have been related to antiplatelet resistance by several large trials, however data from common clinical practice is limited. We examined the influence of previously described polymorphisms, related to aspirin and clopidogrel resistance, on treatment outcome in a real life...
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