Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CYP2C192 and CYP2C93 alleles are associated with stent thrombosis: a case-control study.

European heart journal - 1 Dec 2010

Harmsze Ankie M, van Werkum Jochem W, Ten Berg Jurriën M, Zwart Bastiaan, Bouman Heleen J, Breet Nicoline J, van 't Hof Arnoud W J, Ruven Hendrik J T, Hackeng Christian M, Klungel Olaf H, de Boer Anthonius, Deneer Vera H M

Abstract excerpt

AIMS: despite treatment with clopidogrel on top of aspirin, stent thrombosis (ST) still occurs being the most serious complication after percutaneous coronary interventions (PCIs). In this study, we aimed to determine the effect of variations in genes involved in the absorption (ABCB1 C1236T, G2677T/A, C3435T), metabolism (CYP2C19*2 and *3, CYP2C9*2 and *3, CYP3A4*1B and CYP3A5*3), and pharmacodynamics (P2Y1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angioplasty, Balloon, Coronary
Share to Aspirin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Clopidogrel

Share to Cytochrome P-450 CYP2C19

Share to Cytochrome P-450 CYP2C9

Share to Platelet Aggregation Inhibitors

Share to Stents

Share to Ticlopidine

Source

Identifiers

PMID: 20833683
DOI: 10.1093/eurheartj/ehq321

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP2C19*2 and CYP2C9*3 alleles are associated with stent thrombosis: a case-control study.PMID 20833683Read ↗

Besides CYP2C19*2, the variant allele CYP2C9*3 is associated with higher on-clopidogrel platelet reactivity in patients on dual antiplatelet therapy undergoing elective coronary stent implantation.Semantic proximity Read ↗

CYP2C19*2 genetic polymorphism and incidence of in-stent restenosis in patients on clopidogrel: a matched case-control study.Semantic proximity Read ↗

CYP2C19 phenotype, stent thrombosis, myocardial infarction, and mortality in patients with coronary stent placement in a Chinese population.Semantic proximity Read ↗

CYP2C19*2 genetic polymorphism and incidence of in-stent restenosis in patients on clopidogrel: A matched case-control studySemantic proximity Read ↗

CYP2C19 polymorphisms in acute coronary syndrome patients undergoing clopidogrel therapy in Zhengzhou population.Semantic proximity Read ↗

Paraoxonase-1 is not a major determinant of stent thrombosis in a Taiwanese population.Semantic proximity Read ↗

Effects of genetic variants on platelet reactivity and one-year clinical outcomes after percutaneous coronary intervention: A prospective multicentre registry study.Semantic proximity Read ↗

Cytochrome CYP2C19 polymorphism and risk of adverse clinical events in clopidogrel-treated patients: a meta-analysis based on 23,035 subjects.Semantic proximity Read ↗

Cytochrome P450 CYP 2C19*2 Associated with Adverse 1-Year Cardiovascular Events in Patients with Acute Coronary Syndrome.Semantic proximity Read ↗

Comparison of the effect of CYP2C19 polymorphism on clinical outcome between acute coronary syndrome and stable angina.Semantic proximity Read ↗

Effect of clinical factors and gene polymorphism of CYP2C19*2, *17 and CYP4F2*3 on early stent thrombosis.Semantic proximity Read ↗

Influence of CYP2C19 loss-of-function variants on the antiplatelet effects and cardiovascular events in clopidogrel-treated Chinese patients undergoing percutaneous coronary intervention.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.