Article
A meta-analysis of efficacy and safety of genotype-guided versus standard of care treatment strategies in selecting antiplatelet therapy in patients with acute coronary syndrome.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions - 1 Apr 2021
Nazir Salik, Ahuja Keerat R, Virk Hafeez U H, Elzanaty Ahmed, Waheed Tayyab A, Changal Khalid H, Wohlfarth Kevin, Lakhter Vladimir, Grande Robert D, Eltahawy Ehab A
Abstract excerpt
BACKGROUND: Previous studies have shown similar rates of major adverse cardiovascular events (MACE) in acute coronary syndrome (ACS) patients, treated with P2Y12 inhibitors based on genotype guidance compared to standard treatment. However, given lower than expected event rates, these studies were underpowered to assess hard outcomes. We sought to systematically analyze this evidence using pooled data from...
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