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Article

Genetic determinants of response to clopidogrel and cardiovascular events.

The New England journal of medicine - 22 Jan 2009

Simon Tabassome, Verstuyft Céline, Mary-Krause Murielle, Quteineh Lina, Drouet Elodie, Méneveau Nicolas, Steg P Gabriel, Ferrières Jean, Danchin Nicolas, Becquemont Laurent

Abstract excerpt

BACKGROUND: Pharmacogenetic determinants of the response of patients to clopidogrel contribute to variability in the biologic antiplatelet activity of the drug. The effect of these determinants on clinical outcomes after an acute myocardial infarction is unknown. METHODS: We consecutively enrolled 2208 patients presenting with an acute myocardial infarction in a nationwide French registry and receiving...

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Source

Identifiers

PMID: 19106083
DOI: 10.1056/NEJMoa0808227

Genes

ABCB1
ITGB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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