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Article

Genome-wide association study identifies variants at the IL18-BCO2 locus associated with interleukin-18 levels.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2010

He Meian, Cornelis Marilyn C, Kraft Peter, van Dam Rob M, Sun Qi, Laurie Cathy C, Mirel Daniel B, Chasman Daniel I, Ridker Paul M, Hunter David J, Hu Frank B, Qi Lu

Abstract excerpt

OBJECTIVE: Interleukin-18 (IL-18) is a proinflammatory cytokine involved in the processes of innate and acquired immunities and associated with cardiovascular disease and type 2 diabetes. We sought to identify the common genetic variants associated with IL-18 levels. METHODS AND RESULTS: We perfo...

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Source

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Identifiers

PMID: 20150558
DOI: 10.1161/ATVBAHA.109.199422
PMCID: PMC2841960

Genes

BCO2
NHS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20150558-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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