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Article

Genetic ancestry and population differences in levels of inflammatory cytokines in women: Role for evolutionary selection and environmental factors.

PLoS genetics - 1 Jun 2018

Yao Song, Hong Chi-Chen, Ruiz-Narváez Edward A, Evans Sharon S, Zhu Qianqian, Schaefer Beverly A, Yan Li, Coignet Marie V, Lunetta Kathryn L, Sucheston-Campbell Lara E, Lee Kelvin, Bandera Elisa V, Troester Melissa A, Rosenberg Lynn, Palmer Julie R, Olshan Andrew F, Ambrosone Christine B

Abstract excerpt

Selection pressure due to exposure to infectious pathogens endemic to Africa may explain distinct genetic variations in immune response genes. However, the impact of those genetic variations on human immunity remains understudied, especially within the context of modern lifestyles and living environments, which are drastically different from early humans in sub Saharan Africa. There are few data on population...

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Identifiers

PMID: 29879116
DOI: 10.1371/journal.pgen.1007368
PMCID: PMC5991662

Genes

CCL11
CCL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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