Article
Ascertainment models incorporating effects of variable age of onset.
American journal of medical genetics - 1 Dec 1994
Dawson D V
Abstract excerpt
In pedigree analysis, nonrandom sampling, or ascertainment through affected persons, occurs commonly, making it necessary to adjust appropriately for the ascertainment procedure in order to secure the correct interpretation of results from genetic analysis. Ascertainment models for dichotomous phenotypes are considered for disorders characterized by variable age of onset, particularly considering those instances...
Topics
- Age of Onset
- Algorithms
- Humans
- Models, Genetic
- Pedigree
- Phenotype
- Probability