Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association analysis of dopaminergic gene variants (Comt, Drd4 And Dat1) with Alzheimer s disease.

Journal of biological regulators and homeostatic agents - 1 Jan 2000

Lin W Y, Wu B T, Lee C C, Sheu J J, Liu S H, Wang W F, Tsai C H, Liu H P, Tsai F J

Abstract excerpt

Defects in dopaminergic transmission play important roles in the disturbance of synaptic plasticity and even in advanced cognitive behavior. However, the relationship between genes involved in the regulation of dopamine levels and predisposition for Alzheimer s disease (AD) remains unclear. The potential association of dopamine-modulating gene polymorphisms with AD was evaluated. We performed a case-control study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to Catechol O-Methyltransferase

Share to Dopamine Plasma Membrane Transport Proteins

Share to Haplotypes

Share to Receptors, Dopamine D4

Share to Taiwan

Source

Identifiers

PMID: 23034259

Genes

DRD4
COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association analysis of dopaminergic gene variants (Comt, Drd4 And Dat1) with Alzheimer s disease.PMID 23034259Read ↗

Catechol-o-methyltransferase and Alzheimer's disease: a review of biological and genetic findings.Semantic proximity Read ↗

Genetic polymorphisms involved in dopaminergic neurotransmission and risk for Parkinson's disease in a Japanese population.Semantic proximity Read ↗

Association between polymorphism of COMT gene (Val158Met) with Alzheimer's disease: An updated analysis.Semantic proximity Read ↗

Association between the catechol-O-methyltransferase polymorphism Val158Met and Alzheimer's disease in a Japanese population.Semantic proximity Read ↗

Catechol-O-methyltransferase genetic variant associated with the risk of Alzheimer's disease in a Brazilian population.Semantic proximity Read ↗

Impact of five SNPs in dopamine-related genes on executive function.Semantic proximity Read ↗

Impact of COMT H108L, MAOB int 13 A>G and DRD2 haplotype on the susceptibility to Parkinson's disease in South Indian subjects.Semantic proximity Read ↗

The Role of Single Nucleotide Polymorphisms of Monoamine Oxidase B, Dopamine D2 Receptor, and DOPA Decarboxylase Receptors Among Patients Treated for Parkinson's Disease.Semantic proximity Read ↗

Apathy is associated with a single-nucleotide polymorphism in a dopamine-related gene.Semantic proximity Read ↗

COMT gene and risk for Parkinson's disease: a systematic review and meta-analysis.Semantic proximity Read ↗

Significant association of catechol-O-methyltransferase (COMT) haplotypes with nicotine dependence in male and female smokers of two ethnic populations.Semantic proximity Read ↗

Haplotypes in cathechol-O-methyltransferase gene confer increased risk for psychosis in Alzheimer disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.