Article
Lack of Association Between COMT Polymorphisms and Apathy in Alzheimer's Disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2011
David Renaud, Friedman Leah, Mulin Emmanuel, Noda Art, Le Duff Franck, Kennedy Quinn, Garcia Rene, Robert Philippe H, Yesavage Jerome A, Zeitzer Jamie M
Abstract excerpt
We tested the hypothesis that single nucleotide polymorphisms (SNPs) in catechol-O-methyltransferase (COMT) are associated with apathy in individuals with Alzheimer's disease (AD). We analyzed a cohort of 105 Caucasian individuals with AD (age = 79.3 ± 7.03 years; MMSE = 20.2 ± 4.4) according to...
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