Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-18 gene polymorphisms affect IL-18 production capability by monocytes.

Biochemical and biophysical research communications - 21 Apr 2006

Arimitsu Junsuke, Hirano Toru, Higa Shinji, Kawai Mari, Naka Tetsuji, Ogata Atsushi, Shima Yoshihito, Fujimoto Minoru, Yamadori Tomoki, Hagiwara Keisuke, Ohgawara Tomoharu, Kuwabara Yusuke, Kawase Ichiro, Tanaka Toshio

Abstract excerpt

We previously demonstrated a significant association between IL-18 gene polymorphism 105A/C and asthma. In this study, we investigated the relationship of IL-18 gene polymorphism to IL-18 production capability by monocytes. The frequency of gene polymorphisms including IL-18-105A/C and IL-18--137G/C was determined by PCR analyses. The IL-18 production by monocytes stimulated without or with LPS or A23187+PMA for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma
Share to Interleukin-18

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Monocytes

Share to Polymorphism, Genetic

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 16516851
DOI: 10.1016/j.bbrc.2006.02.096

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL-18 gene polymorphisms affect IL-18 production capability by monocytes.PMID 16516851Read ↗

Association of interleukin-18 gene polymorphism with asthma in Chinese patients.Semantic proximity Read ↗

Association between interleukin-18 gene polymorphism 105A/C and asthma.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in the IL-18 gene with production of IL-18 protein by mononuclear cells from healthy donors.Semantic proximity Read ↗

Interleukin-18 promoter polymorphism and asthma risk: a meta-analysis.Semantic proximity Read ↗

The impact of IL18 gene polymorphisms on mRNA levels and interleukin-18 release by peripheral blood mononuclear cells.Semantic proximity Read ↗

The -137G/C single nucleotide polymorphism in IL-18 gene promoter contributes to tuberculosis susceptibility in Chinese Han population.Semantic proximity Read ↗

Protective role of IL-18 -137G/C polymorphism in a North Indian population with asthma: a pilot study.Semantic proximity Read ↗

Reduced transcriptional activity in individuals with IL-18 gene variants detected from functional but not association study.Semantic proximity Read ↗

Polymorphisms of the IL-18 promoter and bronchial asthma.Semantic proximity Read ↗

Interleukin-18 gene 105A/C genetic polymorphism is associated with the susceptibility of Kawasaki disease.Semantic proximity Read ↗

A Functional Polymorphism in IL-18 Is Associated with Severity of Bronchial AsthmaSemantic proximity Read ↗

Interleukin-18 -607C/A gene polymorphism in Egyptian asthmatic children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.