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Article

Genetic variants of interleukin-18 are associated with reduced risk of atrial fibrillation in a population from Northeast China.

Gene - 30 Aug 2017

Wang Ying-Hui, Fu Lin, Wang Bo, Li Shu-Feng, Sun Zhao, Luan Ying

Abstract excerpt

Atrial fibrillation (AF) affects approximately 1-2% of general population. Chronic inflammation plays an important role in AF development and interleukin-18 (IL-18) is a pro-inflammatory cytokine. This study aimed to assess the association of single nucleotide polymorphisms (SNPs) of IL-18 for with AF risk. Blood samples were taken from 243 AF patients and 160 non-AF individuals from a Chinese population and...

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PMID: 28526653
DOI: 10.1016/j.gene.2017.05.034

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