Article
Response to arsenate treatment in Schizosaccharomyces pombe and the role of its arsenate reductase activity.
PloS one - 1 Jan 2012
Salgado Alejandro, López-Serrano Oliver Ana, Matia-González Ana M, Sotelo Jael, Zarco-Fernández Sonia, Muñoz-Olivas Riansares, Cámara Carmen, Rodríguez-Gabriel Miguel A
Abstract excerpt
Arsenic toxicity has been studied for a long time due to its effects in humans. Although epidemiological studies have demonstrated multiple effects in human physiology, there are many open questions about the cellular targets and the mechanisms of response to arsenic. Using the fission yeast Schizosaccharomyces pombe as model system, we have been able to demonstrate a strong activation of the MAPK Spc1/Sty1 in...
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