Article
Metalloid tolerance based on phytochelatins is not functionally equivalent to the arsenite transporter Acr3p.
Biochemical and biophysical research communications - 2 May 2003
Wysocki Robert, Clemens Stephan, Augustyniak Daria, Golik Pawel, Maciaszczyk Ewa, Tamás Markus J, Dziadkowiec Dorota
Abstract excerpt
Active transport of metalloids by Acr3p and Ycf1p in Saccharomyces cerevisiae and chelation by phytochelatins in Schizosaccharomyces pombe, nematodes, and plants represent distinct strategies of metalloid detoxification. In this report, we present results of functional comparison of both resistance mechanisms. The S. pombe and wheat phytochelatin synthase (PCS) genes, when expressed in S. cerevisiae, mediate only...
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