Article
The MAPK Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast.
Molecular biology of the cell - 1 Oct 2006
Thorsen Michael, Di Yujun, Tängemo Carolina, Morillas Montserrat, Ahmadpour Doryaneh, Van der Does Charlotte, Wagner Annemarie, Johansson Erik, Boman Johan, Posas Francesc, Wysocki Robert, Tamás Markus J
Abstract excerpt
Arsenic is widely distributed in nature and all organisms possess regulatory mechanisms to evade toxicity and acquire tolerance. Yet, little is known about arsenic sensing and signaling mechanisms or about their impact on tolerance and detoxification systems. Here, we describe a novel role of the S. cerevisiae mitogen-activated protein kinase Hog1p in protecting cells during exposure to arsenite and the related...
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