Article
Quantitative transcriptome, proteome, and sulfur metabolite profiling of the Saccharomyces cerevisiae response to arsenite.
Physiological genomics - 19 Jun 2007
Thorsen Michael, Lagniel Gilles, Kristiansson Erik, Junot Christophe, Nerman Olle, Labarre Jean, Tamás Markus J
Abstract excerpt
Arsenic is ubiquitously present in nature, and various mechanisms have evolved enabling cells to evade toxicity and acquire tolerance. Herein, we explored how Saccharomyces cerevisiae (budding yeast) respond to trivalent arsenic (arsenite) by quantitative transcriptome, proteome, and sulfur metabolite profiling. Arsenite exposure affected transcription of genes encoding functions related to protein biosynthesis,...
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