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Article

A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Nov 2008

Kennedy Patrick J, Vashisht Ajay A, Hoe Kwang-Lae, Kim Dong-Uk, Park Han-Oh, Hayles Jacqueline, Russell Paul

Abstract excerpt

Cadmium is a worldwide environmental toxicant responsible for a range of human diseases including cancer. Cellular injury from cadmium is minimized by stress-responsive detoxification mechanisms. We explored the genetic requirements for cadmium tolerance by individually screening mutants from the fission yeast (Schizosaccharomyces pombe) haploid deletion collection for inhibited growth on agar growth media...

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Identifiers

PMID: 18684775
DOI: 10.1093/toxsci/kfn153
PMCID: PMC2563147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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