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Article

Distinct signaling pathways respond to arsenite and reactive oxygen species in Schizosaccharomyces pombe.

Eukaryotic cell - 1 Aug 2005

Rodríguez-Gabriel Miguel A, Russell Paul

Abstract excerpt

Exposure to certain metal and metalloid species, such as arsenic, cadmium, chromium, and nickel, has been associated with an increased risk of cancer in humans. The biological effects of these metals are thought to result from induction of reactive oxygen species (ROS) and inhibition of DNA repair enzymes, although alterations in signal transduction pathways may also be involved in tumor development. To better...

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Identifiers

PMID: 16087744
DOI: 10.1128/EC.4.8.1396-1402.2005
PMCID: PMC1214538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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