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Article

Two variants in the fibulin2 gene are associated with lower systolic blood pressure and decreased risk of hypertension.

PloS one - 1 Jan 2012

Vallvé Joan-Carles, Serra Noemí, Zalba Guillermo, Fortuño Ana, Beloqui Oscar, Ferre Raimon, Ribalta Josep, Masana Lluís

Abstract excerpt

Arterial stiffness is an important factor in hypertension. Fibulin 2 is an extracellular matrix scaffold protein involved in arterial stiffness and, hence, the fibulin 2 (FBLN2) gene may be a candidate for hypertension susceptibility. 4 single nucleotide polymorphisms (SNPs) of FBLN2 were evaluated in an association case-control study containing 447 hypertensive patients and 344 normotensive control subjects. The...

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Source

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Identifiers

PMID: 22912785
DOI: 10.1371/journal.pone.0043051
PMCID: PMC3418224

Genes

FBLN2
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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