Article
Association study of common variations of FBN1 gene and essential hypertension in Han Chinese population.
Molecular biology reports - 1 Jan 2014
Chen Jinfeng, Yang Song, Zhao Xianghai, Shen Jiahui, Wang Hairu, Chen Yanchun, Ji Yanni, Wang Wen, Zhou Wei, Wang Xuecai, Tang Junming, Lu Xiangfeng, Chen Shufeng, Wang Laiyuan, Li Hongfan, Shen Chong, Zhao Yanping
Abstract excerpt
Fibrillin-1 (FBN1) was reported to have impact on the physiological arterial stiffness and vascular remodeling with hypertension of recent years. In the previous study we reported the association of four functional single nucleotide polymorphisms (SNPs) of FBN1 gene and hypertension. Here, we further investigate the association of four tagging SNPs (tagSNPs) which covered remain genetic variation blocks of FBN1...
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