Article
Fibrillin-1 genotype and risk of prevalent hypertension: a study in two independent populations.
Blood pressure - 1 Oct 2012
Jeppesen Jørgen, Berg Nikolaj D, Torp-Pedersen Christian, Hansen Tine W, Linneberg Allan, Fenger Mogens
Abstract excerpt
OBJECTIVE: Mutations in the fibrillin-1 gene are the cause of Marfan syndrome. We wanted to investigate the relationship between a mutation in this gene and risk of prevalent hypertension. METHODS: In a cross-sectional study, the effect of a G-A substitution in intron 27 in the fibrillin-1 gene (rs11856553) on risk of prevalent hypertension was studied in two large population-based studies: the Health 2006 study,...
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