The T-allele of the C825T polymorphism is associated with higher arterial stiffness in young healthy males.

Abstract excerpt

Arterial stiffening is the major cause of increasing systolic blood pressure in arterial hypertension. Increased arterial stiffness is one major mechanism responsible for morbidity and mortality in hypertension. A C825T polymorphism was identified in the gene encoding the G-protein beta3 subunit...

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