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Article

Bone mineral properties in growing Col1a2(+/G610C) mice, an animal model of osteogenesis imperfecta.

Bone - 1 Jun 2016

Masci Marco, Wang Min, Imbert Laurianne, Barnes Aileen M, Spevak Lyudmila, Lukashova Lyudmila, Huang Yihe, Ma Yan, Marini Joan C, Jacobsen Christina M, Warman Matthew L, Boskey Adele L

Abstract excerpt

The Col1a2(+/G610C) knock-in mouse, models osteogenesis imperfecta in a large old order Amish family (OOA) with type IV OI, caused by a G-to-T transversion at nucleotide 2098, which alters the gly-610 codon in the triple-helical domain of the α2(I) chain of type I collagen. Mineral and matrix properties of the long bones and vertebrae of male Col1a2(+/G610C) and their wild-type controls (Col1a2(+/+)), were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27083399
DOI: 10.1016/j.bone.2016.04.011
PMCID: PMC4862917

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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