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Article

Formation of platelet-binding von Willebrand factor strings on non-endothelial cells.

Journal of thrombosis and haemostasis : JTH - 1 Oct 2012

Wang J W, Valentijn J A, Valentijn K M, Dragt B S, Voorberg J, Reitsma P H, Eikenboom J

Abstract excerpt

BACKGROUND AND OBJECTIVE: Von Willebrand factor (VWF) forms strings on activated vascular endothelial cells that recruit platelets and initiate clot formation. Alterations in VWF strings may disturb hemostasis. This study was aimed at developing a flexible model system for structure-function studies of VWF strings. METHODS: VWF strings were generated by inducing exocytosis of pseudo-Weibel-Palade bodies from...

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Share to Blood Platelets
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22905953
DOI: 10.1111/j.1538-7836.2012.04891.x

Genes

VWF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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