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Article

Von Willebrand disease and Weibel-Palade bodies.

Hamostaseologie - 1 Aug 2010

Wang J W, Eikenboom J

Abstract excerpt

Von Willebrand factor (VWF) is a pivotal haemostatic protein mediating platelet adhesion to injured endothelium and carrying coagulation factor VIII (FVIII) in the circulation to protect it from premature clearance. Apart from the roles in haemostasis, VWF drives the formation of the endothelial cell specific Weibel-Palade bodies (WPBs), which serve as a regulated storage of VWF and other thrombotic and...

Topics

Humans
Mutation
Weibel-Palade Bodies
von Willebrand Diseases
von Willebrand Factor

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20680229

Genes

VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Dispatch and delivery at the ER–Golgi interface: how endothelial cells tune their hemostatic responseSemantic proximity Read ↗

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