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Article

How to roll an endothelial cigar: the biogenesis of Weibel-Palade bodies.

Traffic (Copenhagen, Denmark) - 1 Feb 2004

Michaux Grégoire, Cutler Daniel F

Abstract excerpt

Weibel-Palade bodies (WPB) are the regulated secretory organelles of endothelial cells. These cigar-shaped membrane-bound structures function in both hemostasis and inflammation but their biogenesis is poorly understood. Here, we review what is currently known about their formation. The content of WPBs is dominated by the hemostatic factor von Willebrand factor (VWF), whose complex biogenesis ends in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14690496
DOI: 10.1111/j.1600-0854.2004.00157.x

Genes

VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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P‐Selectin and CD63 Use Different Mechanisms for Delivery to Weibel–Palade BodiesSemantic proximity Read ↗

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