Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional architecture of Weibel-Palade bodies

26 Jan 2011

Abstract excerpt

Weibel-Palade bodies (WPBs) are elongated secretory organelles specific to endothelial cells that contain von Willebrand factor (VWF) and a variety of other proteins that contribute to inflammation, angiogenesis, and tissue repair. The remarkable architecture of WPBs is because of the unique properties of their major constituent VWF. VWF is stored inside WPBs as tubules, but on its release, forms strikingly long...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Coagulation and Thrombosis Mechanisms
Share to Cell Adhesion Molecules Research
Share to Platelet Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21266719
DOI: 10.1182/blood-2010-09-267492

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional architecture of Weibel-Palade bodiesPMID 21266719Read ↗

How to roll an endothelial cigar: the biogenesis of Weibel-Palade bodies.Semantic proximity Read ↗

Weibel−Palade bodies at a glanceSemantic proximity Read ↗

Weibel-Palade bodies: a window to von Willebrand disease.Semantic proximity Read ↗

Von Willebrand disease and Weibel-Palade bodies.Semantic proximity Read ↗

von Willebrand factor remodeling during exocytosis from vascular endothelial cells.Semantic proximity Read ↗

Dispatch and delivery at the ER–Golgi interface: how endothelial cells tune their hemostatic responseSemantic proximity Read ↗

Modulation of endothelial organelle size as an antithrombotic strategySemantic proximity Read ↗

BLOC-2 subunit HPS6 deficiency affects the tubulation and secretion of von Willebrand factor from mouse endothelial cells.Semantic proximity Read ↗

Structure modeling hints at a granular organization of the Vertebrate Golgi ribbonSemantic proximity Read ↗

Reduced von Willebrand factor secretion is associated with loss of Weibel-Palade body formation.Semantic proximity Read ↗

Alternative trafficking of Weibel‐Palade body proteins in CRISPR/Cas9‐engineered von Willebrand factor–deficient blood outgrowth endothelial cellsSemantic proximity Read ↗

APOLD1 loss causes endothelial dysfunction involving cell junctions, cytoskeletal architecture, and Weibel-Palade bodies, while disrupting hemostasisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.