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Article

Age and haplotype variations within FADS1 interact and associate with alterations in fatty acid composition in human male cortical brain tissue.

PloS one - 1 Jan 2012

Freemantle Erika, Lalovic Aleksandra, Mechawar Naguib, Turecki Gustavo

Abstract excerpt

UNLABELLED: Fatty acids (FA) play an integral role in brain function and alterations have been implicated in a variety of complex neurological disorders. Several recent genomic studies have highlighted genetic variability in the fatty acid desaturase (FADS1/2/3) gene cluster as an important contributor to FA alterations in serum lipids as well as measures of FA desaturase index estimated by ratios of relevant...

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Source

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Identifiers

PMID: 22900039
DOI: 10.1371/journal.pone.0042696
PMCID: PMC3416866

Genes

FADS1
FADS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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