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Article

DNMT3B promoter polymorphism and risk of immune thrombocytopenic purpura in pediatric Egyptians.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Oct 2012

Shaheen Iman A, Abukhalil Reham E, Ali Dina K, Afifi Rasha A

Abstract excerpt

Idiopathic (immune) thrombocytopenic purpura (ITP) is a heterogeneous clinical disorder characterized by immune-mediated platelet destruction. Epigenetic changes in gene expression, including DNA methylation and histone modifications, might contribute to autoimmunity. Polymorphisms of the DNA methyltransferase 3B (DNMT3B) gene may influence DNMT3B activity on DNA methylation and increase the susceptibility to...

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Share to Child, Preschool
Share to DNA (Cytosine-5-)-Methyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methyltransferase 3B

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Share to Promoter Regions, Genetic

Share to Purpura, Thrombocytopenic, Idiopathic

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Source

Identifiers

PMID: 22885766
DOI: 10.1097/MBC.0b013e32835708ef

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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