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Article

Single nucleotide polymorphism in the methyl-CpG binding domain 4 gene and the risk for immune thrombocytopenic purpura in Chinese population.

Platelets - 1 Jan 2010

Zhao Haifeng, Du Weiting, Wang Donghai, Gu Dongsheng, Xue Feng, Ge Jing, Sui Tao, Yang Renchi

Abstract excerpt

Epigenetics might contribute to autoimmune diseases including immune thrombocytopenic purpura (ITP). Methyl-CpG binding domain protein 4 (MBD4) plays an important role in DNA methylation and transcriptional regulation of gene expression. The polymorphism of the MBD4 gene may influence MBD4 activity on gene expression profiles, thereby influencing individual susceptibility to ITP. To verify this hypothesis, we...

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Source

Identifiers

PMID: 20100009
DOI: 10.3109/09537100903474365

Genes

MBD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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