Article
Activating killer-cell immunoglobulin-like receptors (KIR) and their cognate HLA ligands are significantly increased in autism.
Brain, behavior, and immunity - 1 Oct 2012
Torres Anthony R, Westover Jonna B, Gibbons Cole, Johnson Randall C, Ward David C
Abstract excerpt
Killer-cell immunoglobulin-like receptor (KIR) proteins are expressed on natural killer (NK) cells and appear important in innate and adaptive immunity. There are about 14 KIR genes on chromosome 19q13.4, composed of those that inhibit and those that activate NK cell killing. Haplotypes have different combinations of these genes meaning that not all genes are present in a subject. There are two main classes of...
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