Article
In contrast to other stimulatory natural killer cell immunoglobulin-like receptor loci, several KIR2DS5 alleles predominate in African Americans.
Human immunology - 1 Sept 2009
Hou LiHua, Chen Minghua, Jiang Bo, Kariyawasam Kanthi, Ng Jennifer, Hurley Carolyn Katovich
Abstract excerpt
The five two-domain stimulatory KIR genes carried by 100 random African Americans were characterized by DNA sequencing of genomic DNA covering the majority of coding exons. The frequency of individual loci was similar to that found in European Americans, with the exception of a reduced frequency for KIR2DS1 in African Americans. New alleles were identified at the KIR2DS1 (*008), KIR2DS2 (*006), KIR2DS3 (*00104,...
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