Article
KIR2DL5 alleles mark certain combination of activating KIR genes.
Genes and immunity - 1 Jul 2008
Du Z, Sharma S K, Spellman S, Reed E F, Rajalingam R
Abstract excerpt
Killer cell Ig-like receptors (KIR) control the immune response of NK cells and some T cells to infections and tumors. KIR genes evolve rapidly and are variable between individuals in their number, type and sequence. Here, we determined the nature of KIR2DL5 gene polymorphism in four ethnic groups using direct DNA sequencing method. Nine new sequences were discovered. Within the panel of 248 KIR2DL5-positive...
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