Article
Novel associations between activating killer-cell immunoglobulin-like receptor genes and childhood leukemia.
Blood - 4 Aug 2011
Almalte Zaema, Samarani Suzanne, Iannello Alexandre, Debbeche Olfa, Duval Michel, Infante-Rivard Claire, Amre Devendra K, Sinnett Daniel, Ahmad Ali
Abstract excerpt
Acute lymphoblastic leukemia of pre-B cells (pre-B ALL) is the most frequent form of leukemia affecting children in Western countries. Evidence is accumulating that genetic factors play an important role in conferring susceptibility/resistance to leukemia in children. In this regard, activating killer-cell immunoglobulin-like receptor (KIR) genes are of particular interest. Humans may inherit different numbers of...
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