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Article

Chain-terminating natural mutations affect the function of activating KIR receptors 3DS1 and 2DS3.

Immunogenetics - 1 Oct 2007

Luo Lihui, Du Zeying, Sharma Surendra K, Cullen Rebecca, Spellman Stephen, Reed Elaine F, Rajalingam Raja

Abstract excerpt

To determine the nucleotide polymorphism of activating killer-cell immunoglobulin-like receptors (aKIR) 3DS1 and 2DS3, we developed a novel direct-sequencing method and analyzed DNA samples of 175 KIR3DS1(+) individuals and 72 KIR2DS3(+) individuals from the white population. The putative ligand-binding extracellular immunoglobulin (Ig)-like domains of these aKIR receptors are highly conserved, a scenario...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

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Source

Identifiers

PMID: 17646980
DOI: 10.1007/s00251-007-0239-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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