Article
Genetic associations of killer immunoglobulin like receptors and class I human leukocyte antigens on childhood acute lymphoblastic leukemia among north Indians.
Human immunology - 1 Jan 2016
Misra Maneesh Kumar, Prakash Swayam, Moulik Nirmalya Roy, Kumar Archana, Agrawal Suraksha
Abstract excerpt
BACKGROUND: Molecular interactions between KIRs and their cognate HLA class-I ligands, play a central role in the regulation of natural killer (NK) cell responses in malignancies. We aimed to determine the role of KIR genes and their HLA ligands in genetic predisposition of childhood acute lymphoblastic leukemia (ALL). METHODS: Genotyping of 16 KIR genes, along with HLA class-I groups C1/C2 and Bw4 super-type...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
